Independent testing labs are under tremendous pressure to increase
throughput (production) and detection limits. For samples that are
complex these goals are not congruent with the task of providing
indisputable identification of chemical entities under ultrafast conditions.
While labs must run analyses faster to be competitive, they
cannot sacrifice data quality. This is especially true in highly-regulated
markets such as environmental, food, and pharmaceutical. If an
analyst can't document data quality, the sample analysis information is
considered unusable.
Similarly, R&D and manufacturing support labs must produce
accurate data to protect their company image. This is particularly true
when dealing with complex matrices as found in food, beverage, flavor
and fragrances.
Mass spectrometry manufacturers rely on ion extraction and bestfit,
target compound "library matching" to determine compound identity.
While this works well when dealing with pure standards or clean
samples, the majority of customer samples are far from pure.
A new approach called "deconvolution" – a powerful and proven
mathematical technique for extracting information from background
signals and matrix noise – is revolutionizing the process.
But be forewarned: Not all deconvolution is created equal. This paper
examines the options and details the system requirements needed for
labs to accurately identify compounds, reduce sample prep costs and
reanalysis rates, create ultra-fast screening methods, and dramatically
shorten quantitative run-times.
Download the full-text white paper, "Not All Deconvolution is Created Equal"
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